SYNkinase: Your first choice for small molecule inhibitors


SYN-1163 | CAS 1166393-85-6

PF-4618433 shows improved PYK2 potency, reduced p38 activity, and superior overall selectivity relative to the prototype BIRB796. In the functional osteogenesis assays, cultures treated with increasing concentrations of PF-4618433 starting at day 1 and maintained throughout showed a dose-dependent increases in both alkaline phosphatase activity and mineralization.

In stock
Technical Data
Cas 1166393-85-6
Alternative Names PF-4618433
Salt wt. N/A
References Ref. 1
Ref. 2
Api wt. 445.52
Formula C24H27N7O2
Related Pathways
Purity >95%

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