SYNkinase: Your first choice for small molecule inhibitors


SYN-1077 | CAS 405554-55-4

SB-590885 is a novel, potent and selective small molecule inhibitor of B-Raf kinase, with a Ki of 0.16 nM. It shows an 11-fold greater selectivity for B-Raf over c-Raf. It was used to address the dependence of MAPK signalling and tumor cell growth on B-Raf kinase activity.

In stock
Technical Data
Cas 405554-55-4
Alternative Names SB590885
Salt wt. N/A
References Ref. 1
Ref. 2
Api wt. 453.54
Formula C27H27N5O2
Related Pathways
Purity >95%

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