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PLX4720

SYN-1069 | CAS 918505-84-7

PLX4720 is a potent and selective inhibitor of B-Raf V600E with an IC50 of 13 nM. It is equally potent to c-Raf-1(Y340D and Y341D mutations), and shows 10-fold selectivity for B-Raf V600E over wild-type B-Raf.

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In stock
Technical Data
Cas 918505-84-7
Alternative Names PLX4720
Salt wt. N/A
References Pubmed
Pubmed
Pubmed
Api wt. 413.83
Formula C17H14ClF2N3O3S
Related Pathways
Purity >95%

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