SYNkinase: Your first choice for small molecule inhibitors


SYN-5005 | CAS 870061-27-1

A-839977 is a potent, CNS penetrating P2X7 antagonist whixh blocks BzATP-evoked calcium influx at P2X7 receptors. (IC50 values are 20nM - human, 42nM -rat and 150nM - mouse). A-839977 displays antinociceptive effects in rat and mice models of inflammatory pain.

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Technical Data
Cas 870061-27-1
Alternative Names A-839977
Salt wt. N/A
References Ref. 1
Api wt. 413.26
Formula C19H14Cl2N6O
Related Pathways
Purity >95%

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